Dietary Supplements
Dietary Supplements
The world is experiencing a rapidly aging population since the twenty-first century. The UN projects the world population to reach 9.8 billion in the year 2050, with people over sixty-five reaching more than 1.5 billion, which make up nearly 16% of the population. Another study from WHO shows that only 5% of the population are healthy, 20% suffer from illnesses, and 75% are in various sub-optimal states.
Global aging and the universalization of the sub-optimal health status promote the accelerated market potential of health care products. Statistics show that the global health products industry market is expected to reach 438 billion USD by 2020; this market is expected to reach 600 billion USD by 2026, at a CAGR of 5.94% from 2021 to 2026.
The demand for health care products rapidly increases with the need for healthier well-being. Abiochem embraces this market opportunity to dive into the nutrition and health industry with the utilization of synthetic biology. Currently, Abiochem has made progress in the immunomodulation, anti-aging, and revitalization fields using our biosynthesis technology and comprehensive platforms.
Steviol Glycoside M (Reb M)
As a natural, low-sugar, high-intensity sweetener, Steviol Glycoside M (Reb M) is approximately 200-300 times sweeter than sucrose yet nearly calorie-free. It is widely used across food, beverages, seasonings, baked goods, and dairy products.
Abiochem has overcome the limitations of traditional plant extraction methods by employing synthetic biology to efficiently enzymatically convert high-content steviol glycoside A into Reb M. This breakthrough not only significantly boosts production capacity and reduces costs but also eliminates sensory drawbacks associated with conventional steviol glycosides—such as lingering bitterness, metallic aftertaste, and throat-coating sensation—delivering a healthy sweetener with a pure, clean sweetness to the market.
As the first and only enzymatically converted Reb M product approved by China's National Health Commission, it has secured international certifications including FDA GRAS, HALAL, and HACCP. Recognized as an "Outstanding Innovative Case for Future Industrial Development" by the Ministry of Industry and Information Technology and honored with the CIIF Bio-manufacturing Award, Reb M leverages proprietary core technology to pioneer advancements in food and health innovation.
Human Milk Oligosaccharides (HMOs)
As the third-largest nutritional component and the foremost bioactive substance in breast milk, HMOs play a pivotal role in infant brain development, gut health maintenance, and cognitive enhancement during early growth stages. Their applications span a wide range of fields, including infant formula, food additives, health supplements, foods for special medical purposes (FSMPs), pharmaceutical excipients, and skincare products.
Abiochem's independently developed HMO (2'-FL) received approval from China's National Health Commission in October 2023, marking a pioneering breakthrough in synthetic biology for human milk oligosaccharide products in China. Concurrently, a joint venture was established with the "Mengniu Group" to actively promote the safe application of HMOs in more food products, driving advancements in food nutrition and health. Currently, HMO (2'-FL) has secured GRAS (Generally Recognized as Safe) certification from the U.S. FDA and is expected to obtain EU Novel Food approval as well as Australia-New Zealand certification within 2025.
NMN (β-Nicotinamide Mononucleotide)
As a key precursor to NAD+ (Coenzyme I) in human cells, NMN plays a central role in driving energy and substance metabolism after conversion to NAD+. It is widely applied in fields such as healthy aging, beauty skincare, and health supplements.
Utilizing advanced in vitro synthetic biology technology, Abiochem has developed a proprietary biosynthesis route for NMN, with both the synthesis pathway and enzymes protected by patents. The NMN raw material is produced in Abiochem's own pharmaceutical-grade GMP facility, ensuring stable supply through mass production. The product holds GRAS, HACCP & ISO22000 certifications and has undergone external testing by SGS and Eurofins, guaranteeing reliable quality.
N-Acetylneuraminic Acid (Sialic Acid)
As a highly valuable bioactive substance, N-acetylneuraminic acid (sialic acid) serves as a key active component in bird's nest and breast milk. It offers multiple benefits such as promoting brain development and enhancing immunity, demonstrating significant potential in infant nutrition and health supplements. Amidst rising health-conscious consumption and public demand for efficient nutritional supplementation, it has emerged as a critical functional ingredient for product enhancement and has gained significant market traction.
Abiochem has developed a proprietary synthetic biology production process. Compared to traditional fermentation methods, this technological approach is more advanced, offering advantages including a simpler process, superior quality, and minimal impurities.
In May 2025, Abiochem' self-developed synthetic biology-derived N-acetylneuraminic acid received approval from China's National Health Commission (NHC). This milestone establishes Abiochem as China’s first enterprise authorized to produce novel food ingredient N-acetylneuraminic acid via synthetic biology—a pioneering achievement in the industry.
